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Drug Product Development Internship - Summer 2024

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Takeda

Jan 26, 2024

Applications are closed

  • Internship
    Full-time
    Summer Internship
  • Healthcare
    Science
  • Boston

Requirements

  • Exceptional interpersonal, verbal communication and writing skills.
  • Deadline-driven with an elevated level of organizational and planning skills.
  • Strong quantitative, analytical, problem solving and conceptual skills.
  • Proven record of accomplishment of teamwork, adaptability, innovation, initiative, and integrity.
  • Global mindset to grow in a diverse work environment.
  • Basic understanding of drug development process, experience of working in a scientific lab and use of MS office tools ( Excel, Power Point etc.) is desirable.
  • Currently authorized to work in the United States without sponsorship. Takeda does not provide sponsorship for internship positions.
  • Available to work full-time (40 hours per week), within the core business hours of 8:00am – 5:00pm, for 10-12 weeks during the summer months.
  • Undergraduate, Graduate or PhD, students with specialization in Pharmaceutical Sciences, Chemical Engineering are preferred, with completion of a minimum of one year of university studies.
  • Must be enrolled in school the semester following your internship with Takeda.
  • Please note that Takeda does not provide intern housing or a housing stipend.

Responsibilities

  • The Synthetic Molecules-Drug Product Development (DPD-SM) group is responsible for designing and developing drug product for various stages of human clinical studies leading up to commercialization. As a hands-on technical person, you will carry out the small-scale drug product development activities for synthetic molecules at our internal labs. You will design and develop both oral and injectable formulations. This internship position will be laboratory-based in Cambridge, MA which will primarily involve supporting following projects to be used in the development of Takeda's clinical therapies:
  • Material characterization of granular blends from tablet press to the compaction simulator for improved prediction of tableting performance to enable process optimization, scale up, troubleshooting and tech transfer of manufacturing process for tablet dosage forms. The project would involve working on various unit operations such as mixing, granulation and tableting that are routinely used in the manufacturing process of oral solids. Assessment of physical and in-vitro performance characteristics of tablets are also involved and they include: tensile strength, solid fraction, friability, disintegration and dissolution etc. .
  • Small scale development of soft chewable tablets for pediatric use. Evaluation of co-processed excipients to develop fast disintegrating oral tablets for pediatric use. Assess disintegration and dissolution behavior of these pediatric tablet dosage forms.
  • Formulation Development and scale-up for Lipid Nanoparticles (LNPs). This would include lipid nanoparticle manufacturing using microfluidic mixing, tangential flow filtration and characterizing particle size, zeta potential, encapsulation efficiency, cell viability and transfection.
  • The intern will have the opportunity to work with and present to members of the Drug Product group and other team members within R&D.
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Takeda

Better Health, Brighter Future

Science & Healthcare
Industry
10,001+
Employees

Mission & Purpose

We strive to transform lives. While the science we advance is constantly evolving, our core purpose is enduring. For more than two centuries, our values have guided us to do what’s right for patients and for society. We know that changing lives requires us to do things differently. We start by listening to and addressing what really matters to patients, the people who love them, and those in the healthcare system who provide care. And that’s what inspires us all to be bold, push boundaries and set new standards that open up greater opportunities.