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First-in-Human Dose and Preclinical Pharmacodynamics - Model - Internship - Summer 2024

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Takeda

Jan 26, 2024

Applications are closed

  • Internship
    Full-time
    Summer Internship
  • Healthcare
    Science
  • Boston

Requirements

  • Exceptional interpersonal, verbal communication and writing skills.
  • Deadline-driven with an elevated level of organizational and planning skills.
  • Strong quantitative, analytical, problem solving and conceptual skills.
  • Proven record of accomplishment of teamwork, adaptability, innovation, initiative, and integrity.
  • Global mindset to grow in a diverse work environment.
  • Highly motivated and have strong interests in immunology and oncology drug discovery
  • Strong literature review, analyze and summarize information and oral and written communication skills
  • Deadline-driven with a high level of organizational and planning skills
  • Currently authorized to work in the United States without sponsorship. Takeda does not provide sponsorship for internship positions.
  • Available to work full-time (40 hours per week), within the core business hours of 8:00am – 5:00pm, for 10-12 weeks during the summer months.
  • Graduate student who has completed at least his/her first year of graduate school education with Major in Pharmaceutical Sciences, Pharmacy, and Pharmacology will be preferred. Undergraduate student who has completed at least his/her third year of school education with Major in Pre-med, Pharmaceutical Sciences, Pharmacy, and Pharmacology and has demonstration of literature review and data analyzing skill.
  • Must be enrolled in school the semester following your internship with Takeda.

Responsibilities

  • As a summer intern, the candidate will work with oncology drug discovery scientists and learn critical practice to estimate the first in human dose and the calculation methods for efficacy from syngeneic mouse tumor models (limited to immuno-oncological (IO) drugs for both). The candidates will: 1. Search and summarize FIH dose selection strategy and maximum tolerated dose (MTD) based on targeted cells or MOA for Takeda’s internal IO drug candidates and clinical drug candidates/marketed IO drugs. 2. Search Literature and internal data and summarize the calculation methods for efficacy from syngeneic mouse tumor models and propose the best method for PKPD correlation and translation. The experience will provide valuable experience on literation search, data analysis and provide guidance to critical decisions for drug development.

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