Grad Intern - R&D (Multi-State Protein Design)

Amgen

Nov 26, 2023

Applications are closed

Internship
Full-time
Off-cycle Internship
Science
Research & Development
United States
Remote

Requirements

Basic Qualifications:
Amgen requires that all individuals applying for a grad internship or a co-op assignment at Amgen must meet the following criteria:
18 years or older
Graduated with a Bachelor’s degree from an accredited college or university with a 3.0 minimum GPA or equivalent
Currently enrolled in an MBA program for an MBA internship OR a Master’s program for a Master’s internship OR a PharmD program for a PharmD internship OR Ph.D. for a PhD internship from an accredited college or university and completion of the first year of MBA OR Master’s OR Pharm D OR Ph.D. program before the internship starts
Enrolled in an accredited college or university following the potential internship or co-op assignment
Must not be employed at the time the internship starts
Student must be located in the United States for the duration of the internship OR co-op
Preferred Qualifications:
Degree concentration(s) in Bioengineering, Bioinformatics, Biophysics, Computer Science, or related area
Familiarity with protein design tools (e.g., Rosetta, ProteinMPNN, etc.)
Familiarity with ML protein structure prediction models (e.g., AlphaFold, OmegaFold, IgFold, etc.)
Familiarity with Python
Familiarity with protein structure and protein structure visualization tools (e.g., PyMOL)
Background in computational protein design

Responsibilities

This internship explores protein design methods to combine the power of the newest machine learning tools for structure and sequence generation with the need for compact, stable structures in multi-state design. The successful intern will explore various tools and implementations and evaluate their performance in the single- and multi-state contexts. The final method(s) will then be applied to a novel design problem for conditional/allosteric activation.
As a Grad Intern at Amgen, you will:
assist the team in conducting research, preparing reports, and performing administrative tasks
gain hands-on experience in your chosen field, develop professional skills, and have the opportunity to network with professionals in your industry
have an opportunity to see first-hand how early-stage large molecule drug development is conducted

Amgen

#WeareBiotech

Science & Healthcare

Industry

10,001+

Employees

1980

Founded Year

Mission & Purpose

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.