Intern, Advanced Bioimaging

Denali Therapeutics

Nov 19, 2023

Applications are closed

Internship
Full-time
Summer Internship
Science
San Francisco

Requirements

Currently pursuing a BS, MS, or PhD in Computer Science, Data Science, Bioinformatics, Computational Biology, or related fields
Experience with Python, machine learning frameworks such as scikit-learn, tensorflow, or pytorch, and command line and shell scripting
Strong organizational and communication skills with the ability to work both independently and in a team environment
Experience presenting data analysis methods and results to a small team
Creative and inquisitive thinker who is eager to explore and learn new skills
Preferred:
Experience with image processing and analysis techniques (e.g. signal processing, machine learning, clustering and feature extraction, high dimensional dataset analysis
Experience with parallelization/acceleration libraries such as dask, numba, pycuda, or pyopencl and data pipeline frameworks such as joblib, snakemake, or knime

Responsibilities

Potential projects include one or more of the following:
Design and implement an image processing pipeline to segment and classify cell types and assign them to brain regions in 3D light sheet images
Design and implement a computational pipeline to segment and characterize extended brain structures such as blood vessels, white matter tracts, or ventricles in 3D light sheet images
Develop and characterize methods to scale analyses to multi-terabyte datasets using approaches such as GPU acceleration, high performance computing, or cloud computing
Write reproducible analysis pipelines, contribute to code review, and document, test and deploy code
Collaborate with Discovery Biology and biomarker scientists to develop features and metrics to quantify drug delivery to regions and cell types of interest
Make detailed observations, analyze data, interpret results, and communicate clearly
Present results onsite at cross-functional and departmental meetings as well as at final intern poster session

Denali Therapeutics

Defeat Degeneration

Science & Healthcare

Industry

201-500

Employees

2015

Founded Year

Mission & Purpose

Denali Therapeutics is dedicated to defeating neurodegenerative diseases by breaking through historical barriers in scientific research and clinical development in order to deliver safe and effective medicines to patients and families. Our scientific approach is based on three core principles: rigorous assessment of genetic targets, engineering brain delivery, and using biomarkers to guide development. Our team thrives in a work environment that is scientifically driven, impact-focused, supportive, and collaborative. Our ability to have a positive impact on people’s lives is directly related to the trust we have in each other and our ability to unify our diverse backgrounds and experience behind our purpose to defeat degeneration.