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Summer 2025 Translational Bioinformatics Internship

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Bristol Myers Squibb

Oct 6, 2024

  • Internship
    Full-time
    Summer Internship
  • Data
    Research & Development
  • Summit
  • Quick Apply

AI generated summary

  • You must be a Master/PhD student in a related field with R/Python skills, experience in omics and spatial transcriptomics, and a solid foundation in cancer genomics.
  • You will conduct spatial transcriptome analysis, evaluate cell annotation methods, develop workflows, deploy computational approaches, and present findings for informed decision-making.

Requirements

  • Master or PhD student enrolled in computational biology, bioinformatics, statistics, computer science, data science or related fields.
  • Demonstrable hands-on experience in languages like R or Python including extensive experience with specialized packages core in omics analysis such as Seurat, scVI-tools and Scanyp.
  • Demonstrate experience in Spatial Transcriptomic analysis and deep understanding of cutting these cutting-edge technologies.
  • A strong foundation of biology and keen interest in oncology.
  • A foundational understating on cancer genomics techniques and datasets.
  • Must be able to work full-time for the program duration.
  • Excellent written and verbal communication skills.

Responsibilities

  • Conduct spatial transcriptome analysis using various platforms, such as 10x and Visium.
  • Evaluate Different Cell Annotation and Label Transfer Methods: A key responsibility will be to assess and compare various cell annotation and label transfer techniques, including both single-cell reference-based and reference-free methods. This will involve analyzing the effectiveness and precision of these approaches in different contexts. The intern should have a solid grasp of computational biology and statistical methods to effectively carry out these evaluations.
  • Develop a Systematic Recommendation Workflow for GBM ST analysis: The intern will also be tasked with creating a systematic best practice workflow. This workflow should incorporate the findings from ST analysis and the benchmarking of cell annotation methods, designed to be user-friendly and adaptable for various research needs. Strong skills in data integration and workflow development, as well as clear communication of recommendations, will be essential.
  • Evaluate and deploy cutting edge computational approaches for spatial transcriptome analysis to answer key questions regarding disease biology.
  • Perform analysis and visualizations in a reproducible research framework.
  • Deliver results and present findings for decision making.

FAQs

What is the focus of the Summer 2025 Translational Bioinformatics Internship?

The internship focuses on the dissection of spatial transcriptomic data to understand the interplay between Glioblastoma (GBM) molecular subtypes and the tumor microenvironment (TME).

What skills are required for the internship?

Candidates should have hands-on experience in R or Python and specialized packages for omics analysis, along with a strong foundation in biology and computational biology skills.

What educational background is preferred for applicants?

The internship is aimed at Master or PhD students enrolled in computational biology, bioinformatics, statistics, computer science, data science, or related fields.

Will the intern be expected to develop a workflow?

Yes, developing a systematic recommendation workflow for GBM spatial transcriptomic analysis is a key responsibility of the internship.

Are there any requirements regarding the internship duration?

Yes, the candidate must be able to work full-time for the entire duration of the program.

Is previous experience in Spatial Transcriptomics necessary?

Yes, demonstrable experience in Spatial Transcriptomics analysis and a deep understanding of these technologies are required.

What sort of work environment does Bristol Myers Squibb offer?

Bristol Myers Squibb offers a diverse and inclusive work environment, with opportunities for balancing work and personal life through competitive benefits.

Is the position on-site, remote, or hybrid?

The occupancy type for this role is site-by-design, which may be eligible for a hybrid work model with at least 50% onsite presence at the assigned facility.

Will the intern have the opportunity to present their findings?

Yes, the intern will be expected to deliver results and present findings for decision-making.

What health safety recommendations does Bristol Myers Squibb have for employees?

BMS strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

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Bristol Myers Squibb

Manufacturing & Electronics
Industry
10,001+
Employees

Mission & Purpose

At Bristol Myers Squibb, we work every day to transform patients’ lives through science. That work inspires some of the most interesting, meaningful, and life-changing careers you’ll experience. Join us and pursue innovative ideas alongside some of the brightest minds in biopharma, collaborating with a team rich in diversity of experiences, and perspectives. We have built a sustainable pipeline of potential therapies and are leveraging translational medicine and data analytics to understand how we can deliver the right medicine to the right patient, at the right time, to achieve the best outcome. Whether in a scientific, business or supporting function, a career at BMS means you’ll be inspired every day to grow and thrive through opportunities that are uncommon in scale and scope. Here, you’ll be on the cutting edge of powerful innovation in oncology, hematology, immunology, cardiovascular disease, and fibrosis, with colleagues united in the mission to help patients. Through the Bristol Myers Squibb Foundation, we also promote health equity and seek to improve health outcomes of populations disproportionately affected by serious diseases and conditions. Our mission is to give new hope to help patients prevail over serious disease – it drives everything we do.